Core Facilities

The CQLS Core Laboratory Facilities provides services, technical expertise, and shared-use instrumentation for molecular bioscience research at Oregon State University. The Core Facilities serve as a focal point for acquisition of new instrumentation and development of technologies and services. The lab works closely with the CQLS Biocomputing and Bioinformatics groups which provide advanced computational resources for data mining, data analysis and database development.

The CQLS Core Laboratory has services and instruments in the following areas:

• Genomics – High throughput sequencing Illumina MiSeq and NextSeq 2000; Illumina and PacBio and GBS Library preparation services; 3730 DNA analyzer Sanger sequencing and capillary genotyping and fragment analysis

• DNA/RNA extractions – King Fisher and other types of extractions available

• RNA/DNA QC and Analysis – QC Service instruments including Agilent Bioanalyzer and TapeStation, and Blue Pippen size selection. 

• Droplet Digital PCR – Bio-Rad QX200 droplet digital PCR

• Imaging Resources/Light microscopy – light microscope and confocal laser scanning microscope facility for high resolution analysis

• Shared Instrumentation – BioTek Synergy H1 Plate reader, NanoDrop One spectrophotometer, Qubit, ABI 7500 real-time PCR, Azure c600 Gel Imager, BioRupter, SpeedVac

email lab: lab@cqls.oregonstate.edu or phone: 541-737-3413

Services Sample Dropoff

• Self-serve sample drop off will be moving from ALS 3012 to a BSL1 level room, ALS 3137C, in the next week or so. Typically, we are open between 9am-4pm.
• All samples can be dropped off in the -20C freezer/refrigerator or -80C freezer just inside the front door of ALS 3137C.  There are marked shelves for each service in this freezer. Help will be available by appointment or by ringing a doorbell in ALS 3137C.
• If you need to discuss anything about your samples when dropping them off, please make an appointment ahead of time with the relevant person.
• The BSL2 Core Lab at ALS 3012 will be locked. Use of any of our equipment in ALS 3012 is still by appointment only with the appropriate PPE. You can make an appointment with an individual person or at https://oregonstate.qualtrics.com/jfe/form/SV_eb9Mhwxr0K8OXuC

• The equipment in our multi-user rooms ALS 2156 and ALS 3131, is available for use for trained users . We anticipate consolidating and moving this equipment to the third floor in ALS 3137C sometime summer 2023.
• Apply for instrument room access and training
• Reserve time on the calendar for the instrument. You may need training before access is granted.
• Use of any of our equipment in ALS 3012 is still by appointment only with the appropriate PPE. You can make an appointment or contact an individual person.

Microscopy room (ALS 2070)

Training is needed for both the Zeiss LSM Confocal NLO microscope system and the Keyence BZ-X710 Fluorescence Microscope before access is granted.  The Keyence microscope training information is available online and can be requested. The Zeiss Confocal training is more extensive and is a combination of online and in-person training. Contact Anne-Marie Girard, girarda@cqls.oregonstate.edu for more information