Core Facilities

The CQLS Core Laboratory Facilities provides services, technical expertise, and shared-use instrumentation for molecular bioscience research at Oregon State University. The Core Facilities serve as a focal point for acquisition of new instrumentation and development of technologies and services. The lab works closely with the CQLS Biocomputing and Bioinformatics groups which provide advanced computational resources for data mining, data analysis and database development.

The CQLS Core Laboratory has services and instruments in the following areas:

• Genomics – Short read library preps, GBS library preparation and sequencing on the Illumina MiSeq and NextSeq 2000; Long read library preps for PacBio and services; Sanger sequencing and SSR fragment analysis on the 3730 DNA analyzer.

• DNA/RNA extractions – Animal, plant, soil, King Fisher and custom extractions, High molecular weight DNA extractions

• RNA/DNA QC and Analysis – QC and fragment sizing on the Agilent Bioanalyzer and TapeStation, and Blue Pippen size selection. 

• Microscopy – Keyence BZ-X710 fluorescent microscope, Zeiss LSM 780 NLO Confocal Microscope System

• Shared Instrumentation –  BioTek Synergy H1 Plate reader, NanoDrop One spectrophotometer, Qubit, ABI Absolute Q digital PCR, ABI 7500 real-time PCR, Azure c600 Gel Imager, BioRupter, SpeedVac

email lab: lab@cqls.oregonstate.edu or phone: 541-737-3413

Services Sample Dropoff

• Self-serve sample drop off is in ALS 3139. Hours from 8:30 am - 5 pm
• All samples can be dropped off in the -20C freezer/refrigerator just inside the front door of ALS 3139.  There are marked shelves for each service in this freezer. Help will be available by appointment or by ringing a doorbell in ALS 3139.
• If you need to discuss anything about your samples when dropping them off, please make an appointment ahead of time with the relevant person.

Shared Instrumentation (ALS 3139, ALS 3131)

• The equipment in our multi-user rooms ALS 3139 and ALS 3131, is available for use for trained users.
• Apply for instrument room access and training
• Reserve time on the calendar for the instrument. You may need training before access is granted.
• Use of any of our equipment in ALS 3012 is still by appointment only with the appropriate PPE. You can make an appointment or contact an individual person.

Microscopy room (ALS 2070)

Training is needed for both the Zeiss LSM Confocal NLO microscope system and the Keyence BZ-X710 Fluorescence Microscope before access is granted.  The Keyence microscope training information is available online and can be requested. The Zeiss Confocal training is more extensive and is a combination of online and in-person training. Contact Anne-Marie Girard, girarda@cqls.oregonstate.edu for more information